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Ankylosing spondylitis is a chronic inflammatory disease that mainly affects the joints of the spine, which tend to weld together, causing a limitation of mobility. As a final result there is a loss of flexibility of the column, remaining rigid and fused. It usually appears in men between 20 and 30 years of age and in women, is less frequent and is usually milder.

Ankylosing spondylitis presents as an isolated disease, most of the time, although in some cases it may be associated with a skin disease, called psoriasis or inflammatory bowel diseases.
The cause of ankylosing spondylitis is unknown, but the genes appear to be related.
The disease begins with low back pain that appears and disappears. Such low back pain is present most of the time as the disease progresses.
  • Pain and stiffness are worse at night, in the morning, or when you are not active. The discomfort can wake you up.
  • Pain often improves with exercise or activity.
  • Back pain can begin in the sacroiliac joints (between the pelvis and the spine). Over time, it may compromise all or part of the spine.
  • The lower part of the spine becomes less flexible. Over time, you can stand in a humped forward position.
Other parts of the body that may present stiffness and pain include:
  • The intercostal joints and the sternum, so you can not fully expand the chest.
  • Swelling and pain in the joints of the shoulders, knees and ankles.
  • Swelling and redness of the eye.
Less common symptoms include:
  • Inapetencia
  • Slight fever
  • Weightloss
Ankylosing spondylitis can occur along with other conditions such as:
  • Psoriasis
  • Ulcerative colitis or Crohn's disease
  • Chronic ocular inflammation (iritis)
The patient may also need strong medications to control pain and swelling, such as corticosteroid therapy, short-term use, or TNF inhibitors. Surgery can be performed if pain or joint damage is severe and exercise can help Improve posture and breathing.
For more information, the media
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